Systemic Sclerosis
Keywords:
Systemic Sclerosis, clinical features, case reportAbstract
A case of Systemic Sclerosis is hereby reported, with brief review of literature emphasizing the clinical characteristics and management. Systemic Sclerosis is a connective tissue disorder affecting the skin, blood vessel, and visceral organs. Data relating to the occurrence of scleroderma is sparse or underreported in Liberia. This is a case report of a patient suffering from scleroderma seen at the Jackson F. Doe Regional Referral Hospital, Tappita, Nimba County, Liberia in May, 2018. The goal was to document the clinical occurrence of scleroderma in Liberia. Literature was reviewed using key words including scleroderma, sclerosis, Liberia, West Africa. Data bases searched were AJOL and Pubmed. Clinical manifestations of systemic scleroderma arise from the diffuse deposition of collagen in the skin and visceral organs coupled with vascular injury and immunologic abnormalities. The skin becomes taut resulting in claw like appearance of fingers and a mask like appearance of the face. There are associated orofacial changes resulting in decrease in facial profile, rigidity of tongue and microstomia.
References
Albilia JB, Lam DK, Blanas N, Cloakie CM, Sándor GK. Small mouths big problems? a review of scleroderma and its oral health implications. J Can Dent Assoc 2007;73(9):831836.
Christopher P Denton, MD. Overview and classification of scleroderma disorders. May 2018, UpToDate.
Cazal C,Sobral AP,Neves RF,Freire Filho FW, Cardoso AB, da Silveira MM. Oral complaints in progressive systemic sclerosis: two case reports. Med Oral Patol Oral Cir Buccal 2008;13(2):114118.
de Figueiredo MA, de Figueiredo JA, Porter S. Root resorption associated with mandibular bone erosion in a patient with scleroderma. J Endod 2008;34 (1):102-103.
Özgen M, Koca SS. Sklerodermanýn etiyopatogenezi ve güncel tedavisi. Fýrat Üniv Sað Bil Týp Derg 2010;24(1):69-76.
Dedic A, Pasalic A, Hodzic M, Basovic S, Avdic M, Pasic E. Scleroderma--from the aspect of dental medicine. Med Arh 2011; 65(6):368-370.
Medsger TA Jr, Masi AT. Epidemiology of systemic sclerosis. Ann Intern Med 1971; 74:714-721.
Michet CJ Jr, Mckenna CH, Elveback LR el al. Epidemiology of systemic lupus erythematosus and other connective tissue diseases in Rochester, Minnesota, 1950 through 1979. Mayo C1in Proc 1985; 60:105- 113.
Steen VD, Oddis CV, Conte CG et al. Incidence of systemic sclerosis in Alleghany County. Pennsylvania. A twenty year study of hospital diagnosed cases. 1963-1982. Arthritis Rheum 1997;40:441—445.
Laing TJ, Gillepsie BW, Toth MB et al. Racial differences in scleroderma among women in Michigan. Arthritis Rheum. 1997; 40:734-742
Mayes MD, Lacey N Jr, Beebe-Dimmer J,
Gillepsie BW, Cooper B, Laing TJ,
Scbottenfeld D. Prevalence, incidence, survival and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 2003;48:2246-2255.
Polednak AP. Connective tissue responses in blacks in relation to disease: further observations. Am J Phys Anthropol 1987;74 (3):357- 371.
Kéita S, Mahé A, Traoré DB. Etude rétrospective de 35 cas de sclérodermie systémique à Bamako, Mali. Mali Medical 1996;11: 21-27.
Adelowo OO, Oguntona S. Scleroderma (systemic sclerosis) among Nigerians. Clin Rheumatol 2009;28: 1121-1125.
BR Aka, A. Diabaté, M. Kaloga, HS Kourouma, B.Vagamon, I. Gue. Scleroderma in a Black African Subject: A Study of 217 Cases in Cote d'Ivoire. J Clin Exp Dermatol Res 2017;8: 398.
Itoh M, Yanaba K, Kobayashi T, Nakagawa H. Taxane-induced scleroderma. Br J Dermatol 2007; 156:363.
Systemic sclerosis - case report Alebiosu et al.
Dedic A, Pasalic A, Hodzic M, Basovic S, Avdic M, Pasic E. Scleroderma--from the aspect of dental medicine. Med Arh 2011;65(6):368370.18. White SC, Frey NW, Blaschke DD, Ross MD, Clements PJ, Furst DE, Paulus HE. Oral radiographic changes in patients with progressive systemic sclerosis (scleroderma). J Am Dent Assoc 1977; 94(6):1178-1182.
Yu¨cel ÖÖ, Ercan E. Periodontal conditions and mucogingival surgical treatment of a patient with scleroderma. Hacettepe Diº Hekim Fak Derg 2009;33(1):41-46.20. Neville BW, Damm DD, Allen CM, Bouquot DE. Oral and maxillofacial pathology. 3rd ed, St. Louis, Missouri: Saunders Elsevier, 2009, p.798-801.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Research Journal of Health Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Research Journal of Health Sciences journal is a peer reviewed, Open Access journal. The Journal subscribed to terms and conditions of Open Access publication. Articles are distributed under the terms of Creative Commons License (CC BY-NC-ND 4.0). (http://creativecommons.org/licences/by-nc-nd/4.0). All articles are made freely accessible for everyone to read, download, copy and distribute as long as appropriate credit is given and the new creations are licensed under the identical terms.
