Assessment of quality of life among patients attending HIV clinics in Ilorin metropolis
Keywords:
Quality of life, Human Immunodeficiency Virus, Patients, Anti-Retroviral TherapyAbstract
Objectives: The Sub-Saharan Africa (SSA), is being hit hard by the epidemic of Acquired Immunodeficiency Syndrome (AIDS) and carries the globe's heaviest burden of HIV/AIDS. HIV/AIDS has been transformed into a chronic condition, albeit one with no cure, making it important to assess determinants of quality of life (QoL) and, if required, improve the QoL of People Living with HIV (PLHIV). The study assessed the determinants of quality of life of patients attending HIV clinics in Ilorin metropolis.
Methods: The study was a descriptive cross sectional study. A sample size of 384 HIV positive patients who were systematically recruited at the 5 public service delivery sites in Ilorin. Data was analyzed using SPSS software version 20.0. Level of significance was pre-determined at p-value < 0.05 at a confidence level of 95%.
Results: Majority 213 (55.5%) of the respondents had good QoL, while 171 (44.5%) had low QoL with overall Mean score of 68±14. This study showed that being employed, high income, and low cost of care were associated with good health related (HRQoL). Regression analysis revealed that age > 30yrs (odds = 1.5), longer duration on Highly Active Anti-retroviral Therapy (HAART) >3yrs (Odds = 1.5), CD4 count >500cells/mm3 (Odds = 1.2), high monthly income (Odds=1.6) and low cost of care (Odds= 1.27) were found to determine good QoL.
Conclusion: Government should therefore expand access to HIV care by considering more Primary Health Care facilities as Anti-Retroviral Therapy ( ART) treatment centers.
References
National Population Commission - NPC/Nigeria,
ICF international. Nigeria Dempgraphic and Health Survey 2013, Abuja, NPC/Nigeria and ICF international 2014.
Drummond M.F, Schulper M.J, Torrance G.W, O'Brien B.J, (2005) SGL. Methods for the
Economic Evaluation of Health Care Programmes. 3rd ed ed. Oxford, UK:: Oxford University Press.; 2005.
Murray C.J.L AAK. Understanding DALYs.
Journal of Health Economics. 1997;16(6):703-30.
Doris M.M AK, Faith M, Janet S, Albert W.W, .
Factors That Affect Quality of Life among People Living with HIV Attending an Urban Clinic in Uganda: A Cohort Study. PLOS ONE. 2015.
Mills E.J BC, Birungi J, Chan K, Ford N, Cooper C.L, et al. Life Expectancy of Persons Receiving
Combination Antiretroviral Therapy in LowIncome Countries: A Cohort Analysis From Uganda. Annals of Internal Medicine. 2011;155(4):209-16.
Wu A.W. Quality of life assessment comes of age in the era of highly active antiretroviral therapy. AIDS. 2000;14:1449-51.
Murri R FM, Del B.C, Visona R, Barracco A, Zambelli A, et al. Determinants of health-related quality of life in HIV-infected patients. AIDS Care. 2003;15(4):581-90.
De Castro N, Braun J, Charreau I, Pialoux G, Cotte L, Katlama C. Switch from Enfuvirtide to Raltegravir in Virologically Suppressed
Multidrug-Resistant HIV-1-Infected Patients: A
Randomized Open-Label Trial. Clinical
Infectious Diseases. 2009;49:1259-67.
Briongos F.L.S BLP, Palacios M.T, González S.M, Eiros B.J.M Assessment of factors influencing health-related quality of life in HIVinfected patients. HIV Medicine. 2011;12:22-30.
Jelsma J ME, Hughes J, Tinise X, Darder M. An investigation into the health-related quality of life of individuals living with HIV who are receiving HAART. AIDS Care. 2005;17:579-88.
Bopp C.M, Phillips K.D, Fulk L.J, Hand G.A. Clinical implications of therapeutic exercise in HIV/AIDS. J Assoc Nurses AIDS Care. 2003;14(1):73-8.
UNGASS, country, progress, report. Nigeria; 2010.
Dropulic B, Humeau L, Binder G.K, Lu X, Slepushkin V, Merling R, et al. HIV-1-derived lentivirus vector-based antisense gene therapy:towards an alternative treatment for HIV/AIDS. Mol Ther. 2004;9(1003):384.
Federal Republic of Nigeria. Global AIDS Response Country Progress Report. Nigeria2012.
Braitstein P. Mortality of HIV-1-infected patients in the first year of antiretroviral therapy: comparison between low-income and highincome countries. Lancet. 2006;367(9513):817-24.
Badri M, Lawn S.D, Wood R. Short-term risk of AIDS or death in people infected with HIV-1 before antiretroviral therapy in South Africa: a l o n g i t u d i n a l s t u d y . L a n c e t .
;368(9543):1254-9.
Jerene D, et, al. Predictors of early death in a cohort of Ethiopian patients treated with HAART. BMC Infect Dis. 2006;6(136).
Etard JF, et, al. Mortality and causes of death in adults receiving highly active antiretroviral therapy in Senegal: a 7-year cohort study. Aids. 2006;20(8):11181-9.
Bjarne R, Jan A O. The health related quality of life of people living with HIV/AIDS in subSaharan Africa - a literature review and focus group study. Cost Effectiveness and Resource Allocation 2010;8(5).
Healtlh KSMo. HIV M& E. In: HIV Unit E, editor. 2015.
MO A. Sample size determination. Research Methodology with statistics for health and social sciences. Ilorin: mathadex; 2003. p. 118-20.
Lara AM. Utility assessment of HIV/AIDSrelated health states in HIV-infected Ugandans. AIDS. 2008;22(1):123-30.
Moreland S, Namisango E, Paxton A, Powell RA. The costs of HIV treatment, care and support services in Uganda. Measure Evaluation, February, 2013.
WHO, UNAIDS, UNICEF. 'Towards universal access: scaling up priority HIV/AIDS interventions in the health sector'. 2008.
Sekabira R N-MJ, Makumbi F, Kiwanuka N, Kiweewa F, Wambwire Mangen F Determinants of Health-Related Quality of Life among Adults in Routine HIV Care,2012; 1:515 2012 515 Contract No.: 515.
Stangl A.L WN, Mermin J, Awor A.C, Bunnell R.E. Trends and predictors of quality of life among HIV-infected adults taking highly active antiretroviral therapy in rural Uganda. AIDS Care. AIDS Care. 2007;19:626-36.
WHO/UNAIDS/UNICEF. 'Towards Universal Access: Scaling up priority HIV/AIDS interventions in the health sector'. 2010.
Hubben G.A.A, Bishai D, Pechlivanoglou P, Cattelan A.M, Grisetti R, Facchin C, et al. The societal burden of HIV/AIDS in Northern Italy: An analysis of costs and quality of life, . AIDS Care: Psychological and Socio-medical Aspects of AIDS/HIV,. 2008;20(4):449-55.
Herrmann S ME, Hyland N.B, Lalanne C, Mallal S, Nolan D, Chassany O, Duracinsky M,. HIVrelated stigma and physical symptoms have a persistent influence on health-related quality of life in Australians with HIV infection. Health Qual Life Out 2013;11.
Preau M MF, Carrieri M.P, Lert F, Obadia Y, Spire B. Health-related quality of life in French people living with HIV in 2003: results from the national ANRS-EN12-VESPA Study. AIDS. 2007;21:1927.
Serovich JM. A test of two HIV disclosure theories. Aids Educ Prev 2001;13:355-64.
Geocze L MS, De Marco MA, Nogueira-Martins LA, Citero VD. Quality of life and adherence to HAART in HIV-infected patients. Rev Saude Publ. 2010;44(7):43–749.
Este J.A CT. Current status and challenges of antiretroviral research and therapy. Antivir Res. 2010;85:25-33.
Airoldi M ZM, Bisi L, Bini T, Antinori A, Mussini
C, Bai F, Orofino G, Sighinolfi L, Gori A, Suter F, Maggiolo F. One-pill once-a-day HAART: a simplification strategy that improves adherence and quality of life of HIV-infected subjects Patient Prefer Adherence 2010;4:115-25.
Zinkernagel C TP, Rickenbach M, Amiet R, Ledergerber B, Volkart A.C, Rauchfleisch U, Kiss
A, Werder V, Vernazza P, Battegay M. Swiss HIV Cohort Study: Importance of mental health assessment in HIV-infected outpatients. J Acquir Immune Defic Syndr. 2001;28:240-9.
Rueda S RJ, Mustard C, Bayoumi A, Lavis J.N, Rourke S.B,. Employment status is associated with both physical and mental health quality of life in people living with HIV. . Aids Care 2011;23:435-43.
Call S.A KJC, Stewart K.E, Westfall A.O, Mallinger A.P, DeMasi R.A, Centor R, Saag M.S. Health-related quality of life and virologic outcomes in an HIV clinic. . Qual Life Res 2000;9:977-85
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Research Journal of Health Sciences
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Research Journal of Health Sciences journal is a peer reviewed, Open Access journal. The Journal subscribed to terms and conditions of Open Access publication. Articles are distributed under the terms of Creative Commons License (CC BY-NC-ND 4.0). (http://creativecommons.org/licences/by-nc-nd/4.0). All articles are made freely accessible for everyone to read, download, copy and distribute as long as appropriate credit is given and the new creations are licensed under the identical terms.
