Exploring atypical manifestations of Mpox: Anarrative review
Keywords:
Monkey pox, Mpox, Atypical manifestations, Mpox virus, NigeriaAbstract
Mpox (formerly referred to as monkey pox), a viral infection known for its
characteristic manifestations, presents with atypical symptoms, leading to
diagnostic and management challenges. Recent outbreaks of the disease have
also revealed changes in the epidemiologic patterns of the disease with many
cases going unnoticed. These scenarios if not properly identified and addressed
can led to increased healthcare burden created by the virus. To conduct the
narrative review of the concerned literature, a comprehensive and well through
search from PUBMED, Google scholar, EMBASE and African Journal Online
Evaluating Studies was conducted from published works between 2003 to 2023.
This narrative review aims at exploring the atypical manifestations of Mpox, by
reviewing various manifestations of the disease, examining the overlying
mechanisms and factors influencing these manifestations; and more so,
assessing various clinical implications and challenges facing its management,
with the hope of suggesting future directions in tackling the clinical implications
and challenges. Regarding the atypical manifestations of Mpox, the review
focused on the neurological, dermatological, and respiratory presentations,
highlighting the diverse symptoms observed in each case. In addition, accurate
diagnosis of atypical cases is crucial and requires a high index of suspicion,
comprehensive differential diagnosis, and appropriate diagnostic testing.
Tailored strategies for treatment are essential to address the specific
manifestations observed. For future research, a focus on elucidating the
pathogenesis, identifying risk factors, improving diagnostic approaches, and
evaluating treatment strategies for atypical Mpox cases is required.
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