Prevalence of Metabolic Syndrome among Chronic Kidney Disease patients attending a tertiary hospital in Nigeria – a Cross - Sectional Study
Keywords:
Metabolic syndrome, chronic kidney disease, diabetes mellitusAbstract
Objective: Metabolic syndrome and chronic kidney disease are major public health challenges. This study aimed at determining the prevalence of metabolic syndrome among chronic kidney disease patients.
Methods: One hundred and sixty patients were enrolled. Glomerular filtration rates were estimated using the Cockcroft Gault formula. Metabolic syndrome was defined by the presence of ≥ 3 of the following: Central obesity (waist circumference of >102 cm in males or >88 cm in females); Hypertriglyceridemia >150 mg/dL, low HDL cholesterol (<40 mg/Dl in males and <50 mg/dL in females), Hypertension (>130/85mmHg), Fasting plasma glucose >100 mg/dL.
Results: The overall prevalence of metabolic syndrome was 67.5%, CKD stage 5 had the highest prevalence (85.1%) (p = 0.165). Prevalence among diabetics was 82% (p <0.000). CKD stage and number of metabolic syndrome criteria positively correlated.
Conclusion: approximately seven out of every 10 CKD patients had metabolic syndrome. It was more associated with advanced CKD. Diabetics compared to non-diabetics were 1.5 times more predisposed.
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